Cardio Renal Failure

Cardiorenal syndrome (CRS) commonly occurs during treatment of acute decompensated heart failure (ADHF) and is associated with poor clinical outcome. The pathophysiology of CRS entails a complex interaction between hemodynamic alterations, including reduced renal perfusion, increased venous pressure and activation of multiple Neurohormonal systems. Attempts to effectively treat congestion while preserving renal function in ADHF are often met with limited clinical success and often require therapeutic decisions that reflect a compromise between potential benefits and harm. Cardio renal syndromes (CRS) have been subdivided into five syndromes representing clinical vignettes in which both the heart and the kidney are involved in bidirectional injury and dysfunction via a final common pathway of cell-to-cell death and accelerated apoptosis mediated by a variety of mechanisms including ischemia, inflammation, and oxidative injury.

  • Acute cardio renal syndrome
  • Pathophysiology
  • Congestion in the cardio-renal
  • Cardiorenal versus Reno cardiac syndrome

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