Mineral and Bone Disorders

Mineral and bone disorder in chronic kidney disease (CKD) occurs when damaged kidneys and abnormal hormone levels cause calcium and phosphorus levels in a person's blood to be out of balance. Mineral and bone disorder commonly occurs in people with CKD and affects most people with kidney failure receiving dialysis. Chronic kidney disease is kidney damage that occurs slowly over many years, often due to diabetes or high blood pressure. Once damaged, the kidneys can’t filter blood as they should. This damage can cause wastes to build up in the body and other problems that can harm a person’s health, including mineral and bone disorder. The kidneys play an important role in maintaining healthy bone mass and structure by balancing phosphorus and calcium levels in the blood. Healthy kidneys activate a form of vitamin D that a person consumes in food, turning it into calcitriol, the active form of the vitamin. Calcitriol helps the kidneys maintain blood calcium levels and promotes the formation of bone. The kidneys also remove extra phosphorus, helping balance phosphorus and calcium levels in the blood. Keeping the proper level of phosphorus in the blood helps maintain strong bones.

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    4th World Kidney Congress

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